“None of the residual ‘dregs’ that we used for this work came from vaccines that could have been otherwise administered. “This project did not waste vaccine material or reduce in any way the number of vaccine doses available to the public,” they told Motherboard. “For this work, RNAs were obtained as discards from the small portions of vaccine doses that remained in vials after immunization such portions would have been required to be otherwise discarded and were analyzed under FDA authorization for research use,” they said.įire and Shoura explained that none of what they studied came from usable vaccines. The scientists were light on details about how they acquired the Moderna sample. Knowing these sequences and having the ability to differentiate them from other RNAs in analyzing future biomedical data sets is of great utility.” “As the vaccine has been rolling out, these sequences have begun to show up in many different investigational and diagnostic studies. We posted the putative sequence of two synthetic RNA molecules that have become sufficiently prevalent in the general environment of medicine and human biology in 2021,” they told Motherboard in an email. Standard methods facilitate such sequencing.”Īccording to Stanford scientists Andrew Fire and Massa Shoura, this isn’t technically “reverse-engineering” a vaccine. “Despite their ubiquity, sequences are not always available for such RNA. “RNA vaccines have become a key tool in moving forward through the challenges raised both in the current pandemic and in numerous other public health and medical challenges,” the scientists said on GitHub. The first two are an explanation by the team of scientists about the work, the second two pages are the entire mRNA sequence for the Moderna COVID-19 vaccine.
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